Safety Alerts & Recalls

Search all Safety Alerts & Recalls

Latest Alerts

Newer Antipsychotics Associated with Significant Weight Gain With Short-Term Use in Children and Adolescents
An article recently published in the Journal of the American Medical Association links the newer atypical antipsychotics such as aripiprazole (Abilify), olanzapine (Zyprexa), quetiapine (Seroquel), and risperidone (Risperdal), with weight gain and increases in insulin, glucose, cholesterol, and triglyceride levels in children and adolescents age 4 to 19 years who took these medicines for 11 weeks. By the end of this study, patient weight increased by 18.7 pounds with olanzapine (Zyprexa), by 13.4 pounds with quetiapine (Seroquel), by 11.7 pounds with risperidone (Risperdal), and by 9.7 pounds with aripiprazole (Abilify). Antipsychotics are becoming more commonly used for many different mood and behavior conditions, especially in children, adolescents, and young adults. Although FDA approvals vary by drug, the newer antipsychotics are used for a variety of psychological conditions, including schizophrenia, autism, and bipolar disorder. However, they are also prescribed "off-label" to treat attention deficit hyperactivity disorder (ADHD) and other mood and behavior disorders. For more information, please visit: http://jama.ama-assn.org/cgi/content/short/302/16/1765?home
Learn More

Newer Antipsychotics Associated with Significant Weight Gain With Short-Term Use in Children and Adolescents
An article recently published in the Journal of the American Medical Association links the newer atypical antipsychotics such as aripiprazole (Abilify), olanzapine (Zyprexa), quetiapine (Seroquel), and risperidone (Risperdal), with weight gain and increases in insulin, glucose, cholesterol, and triglyceride levels in children and adolescents age 4 to 19 years who took these medicines for 11 weeks. By the end of this study, patient weight increased by 18.7 pounds with olanzapine (Zyprexa), by 13.4 pounds with quetiapine (Seroquel), by 11.7 pounds with risperidone (Risperdal), and by 9.7 pounds with aripiprazole (Abilify). Antipsychotics are becoming more commonly used for many different mood and behavior conditions, especially in children, adolescents, and young adults. Although FDA approvals vary by drug, the newer antipsychotics are used for a variety of psychological conditions, including schizophrenia, autism, and bipolar disorder. However, they are also prescribed "off-label" to treat attention deficit hyperactivity disorder (ADHD) and other mood and behavior disorders. For more information, please visit: http://jama.ama-assn.org/cgi/content/short/302/16/1765?home
Learn More

Receive Safety Alerts & Recalls by email or text message.

Register

Date Published Title Drug Source
2009-10-29 Newer Antipsychotics Associated with Significant Weight Gain With Short-Term Use in Children and Adolescents Quetiapine MediGuard CRT
2009-10-28 Newer Antipsychotics Associated with Significant Weight Gain With Short-Term Use in Children and Adolescents Olanzapine MediGuard CRT
2009-10-28 Newer Antipsychotics Associated with Significant Weight Gain With Short-Term Use in Children and Adolescents Aripiprazole MediGuard CRT
2009-10-28 Recall of All Accusure Insulin Syringes Insulin Glargine FDA
2009-10-28 Recall of All Accusure Insulin Syringes Insulin Lispro FDA
2009-10-28 Recall of All Accusure Insulin Syringes Insulin Aspart FDA
2009-10-28 Recall of All Accusure Insulin Syringes Insulin Manufacturer
2009-10-26 Update on Risk of Progressive Multifocal Leukoencephalopathy (PML) with Use of Rituxan Rituximab FDA
2009-10-25 Recall of Several Lots of Teva / Ivax Atenolol 25 mg and 50 mg Tablets Atenolol FDA
2009-10-25 Recall of a Single Lot of Actavis / Catalent Bupropion Extended-Release Tablets 150 mg Bupropion FDA
2009-10-23 Recall of Two Lots of Cytomel 25 mcg (Liothyronine) Tablets Liothyronine FDA
2009-10-23 Recall of Several Acetaminophen Products Acetaminophen FDA
2009-10-18 Recall of Single Lot of Advair Diskus 100/50mcg Fluticasone Propionate with Salmeterol FDA
2009-10-18 Three Lots of Lac-Hydrin Recalled Ammonium Lactate FDA
2009-10-18 Single Lot of Naproxen 500 mg Tablets Recalled Naproxen FDA
2009-10-14 FDA Warns Companies to Stop Making Unapproved Codeine Sulfate Tablets Codeine FDA
2009-09-30 Recall of Single Lot of Dr. Reddy's Citalopram 40 mg Tablets Citalopram Manufacturer
2009-09-30 Recall of Single Lot of Dr. Reddy's Fexofenadine 180 mg Tablets Fexofenadine Manufacturer
2009-09-30 Recall of Single Lot of Dr. Reddy's Pravastatin 10 mg Tablets Pravastatin Manufacturer
2009-09-30 Recall of Single Lot of Dr. Reddy's Risperidone (plain) 25 mg Tablets Risperidone Manufacturer